郭勇，南华大学特聘教授，博士生导师，南华大学“青年优秀人才”。2005年——2014年，本、硕博就读于西北农林科技大学。主要从事天然活性成分的发现、结构优化、生物活性及构效关系研究。主持国家自然基金—面上、青年基金项目、河南省优秀青年科学基金、河南省省级联合基金、河南省自然科学基金面上（2项）、中国博士后面上项目、河南省博士后（一等）等多项项目。以第一和通讯作者先后在 J. Med. Chem., Eur. J. Med. Chem., Eur. J. Pharm. Sci., J. Agri. Food Chem., Ind. Crop Prod., Bioorg. Med. Chem.等SCI期刊发表论文40多篇，其中中科院1区Top 20篇，ESI高被引1篇。

1. Yang, R., Cheng, W., Huang, M., Xu, T., Zhang, M., Liu, J., Qin, S., Guo, Y*. Novel membrane-targeting isoxanthohumol-amine conjugates for combating methicillin-resistant Staphylococcus aureus (MRSA) infections. European Journal of Medicinal Chemistry, 2024, 116274.

2. Yao, H., Cui, L., Liu, H., Li, X., Shen, L., Yang, R.*, Qin, S*., Guo, Y*. Quinoline-based anti-MRSA agents: Current development, structure-activity relationships, and mechanisms. Chinese Chemical Letters, 2024, 108511.

3. Cheng, W., Xu, T., Cui, L., Xue, Z., Liu, J., Yang, R.*, Qin, S*., Guo, Y*. Discovery of Amphiphilic Xanthohumol Derivatives as Membrane-Targeting Antimicrobials against Methicillin-Resistant Staphylococcus aureus. Journal of Medicinal Chemistry, 2023, 66(1), 962-975.

4. Yang, R., Hou, E., Cheng, W., Yan, X., Zhang, T., Li, S., Yao, H.*, Liu, J.*, Guo, Y*. Membrane-targeting neolignan-antimicrobial peptide mimic conjugates to combat methicillin-resistant Staphylococcus aureus (MRSA) infections. Journal of Medicinal Chemistry, 2022, 65(24), 16879-16892.

5. Guo, Y*., Hou, E., Wen, T., Yan, X., Han, M., Bai, L. P., Liu, J.*, Qin, S*. Development of membrane-active honokiol/magnolol amphiphiles as potent antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). Journal of Medicinal Chemistry, 2021, 64(17), 12903-12916.

招生方向：药学、天然药物化学

热烈欢迎对中药活性成分提取分离、天然产物结构优化、小分子药物合成、有机化学、抗感染药物材料及抗感染药理感兴趣的博士后、博士、硕士研究生以及本科生加入本课题组！

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