一、基本情况
卢瑞瑞，中药学博士，讲师，硕士生导师。主要研究方向为中药治疗肾脏疾病的作用及机理。主持国家自然科学基金青年项目，湖南省自然科学基金青年项目，南华大学博士科研启动基金项目。在国际权威期刊发表SCI论文数篇。
二、研究领域
1.中药治疗肾脏疾病的作用及机理
2.中药治疗肾脏疾病的物质基础研究
三、工作及学习经历
2022/6-至今，南华大学，药学院，讲师
2018/9--2021/6，广州中医药大学-山东大学，联合培养，博士
2015/9-2018/6，广州中医药大学，硕士
2011/6-2015/9，新疆医科大学，学士
四、教学工作
目前承担本科生课程：中医药学概论、生药学等
五、承担课题
1. 国家自然科学基金青年项目（82404990），30万，2025.1-2027.12，在研，主持；
2. 湖南省自然科学基金青年项目（2023JJ40563），5万，2023.1-2025.12，在研，主持；
3. 南华大学博士科研启动基金（220XQD107），10万，2023-2026，在研，主持。
六、代表性文章
1) Ruirui Lu; Jie Zhou; Bihao Liu; Ning Liang; Yu He; Lixia Bai; Peichun Zhang; YanchunZhong; Yuan Zhou; Jiuyao Zhou; Paeoniflorin ameliorates Adriamycin-induced nephrotic syndrome through the PPARγ/ANGPTL4 pathway in vivo and vitro, Biomedicine & Pharmacotherapy, 2017, 96: 137-147;
2) Ruirui Lu; Junqi Chen; Bihao Liu; Hua Lin; Lixia Bai; Peichun Zhang; Dandan Chen;Honglian Li; Jicheng Li; Yu Pang; Yuan Zhou; Jiuyao Zhou; Junbiao Wu; Protective role of Astragaloside IV in chronic glomerulonephritis by activating autophagy through PI3K/AKT/AS160pathway, Phytotherapy Research, 2020, 34(12): 3236-3248;
3) Ruirui Lu; Xu Yan; Guoxing Fang; Yuming Zhuang; Lulu Guo; Chao Zhang; Xiang Wu; Peng Xiao; Yiwen Cao; Fan Yang; Xiao Yu; Jin-peng Sun; Jiu-yao Zhou; A molecular mechanism of UDCA engagement with GPBAR and subsequent G protein interaction revealed by scattered alanine scanning, Biochemical and Biophysical Research Communications, 2022, 600: 14-21;
4) Bihao Liu; Ruirui Lu; Honglian Li; Yuan Zhou; Peichun Zhang; Lixia Bai; Dandan Chen;
Junqi Chen; Jicheng Li; Yu Li; Junbiao Li; Chunling Liang; Jianping Song; Xusheng Liu; Jiuyao
Zhou; Zhen-wu-tang ameliorates membranous nephropathy rats through inhibiting NF-κB pathway and NLRP3 inflammasome, Phytomedicine, 2019, 59: 152913;
5) Fan Yang; Chunyou Mao; Lulu Guo; Jingyu Lin; Qianqian Ming; Peng Xiao; Xiang Wu; Qingya
Shen; Shimeng Guo; Dan-Dan Shen; Ruirui Lu; Linqi Zhang; Shenming Huang; Yuqi Ping; Chenlu Zhang;Cheng Ma; Kai Zhang; Xiaoying Liang; Yuemao Shen; Fajun Nan; Fan Yi; Vincent C. Luca; Jiuyao Zhou; Changtao Jiang; Jin-Peng Sun; Xin Xie; Xiao Yu; Yan Zhang ; Structural basis of GPBAR activation and bile acid recognition, Nature, 2020, 587(7834): 499-504;
6) Qin Li; Guolong Peng; Huimei Liu; Liwen Wang; Ruirui Lu*; Lanfang Li*; Molecular mechanisms of secretory autophagy and its potential role in diseases, Life sciences, 2024,122653;
7) Huimei Liu; Hui Mao; Xueqian Ouyang; Ruirui Lu*; Lanfang Li*; Intercellular Mitochondrial Transfer: The Novel Therapeutic Mechanism for Diseases; Traffic, 2024,25, e12951;
8) Huimei Liu; Lanfang Li*; Ruirui Lu*; ZIP transporters‐regulated Zn2+ homeostasis: A novel determinant of human diseases; Journal of cellular physiology, 2024,1-24.