一、基本情况
江金环，中药学博士；讲师，硕士生导师。主要从事小分子药物抗肿瘤、抗炎等研究。参与国家自然科学基金面上项目1项，主持湖南省自然科学基金青年项目、湖南省教育厅一般项目、衡阳市科技厅指导项目、南华大学博士启动金项目等多项科研项目。近年来，以第一或通讯作者发表SCI学术论文10余篇，其中高被引论文1篇，参与作者论文多篇。
Email: jjhuan1116@163.com
二、研究领域
1.小分子药物抗肿瘤、抗炎等机制研究
2.靶向修饰纳米粒作为药物传递系统的研究
三、工作及学习经历
2019/5-至今，南华大学，药学院，讲师
2015/9-2019/2，澳门科技大学，中医药学院 博士
四、社会兼职
中国药理学会教学与科普专业委员会青年委员
Frontiers in Bioengineering and Biotechnology，Frontiers in pharmacology等杂志客座编辑。
五、教学工作
主讲药理学、机能实验学、临床药物治疗学等课程。主持南华大学教学改革研究重点项目、船山学院教学改革研究一般项目等，以第一作者发表教学改革论文3篇。
六、承担课题
1. 湖南省自然科学基金：2021JJ40474，主持，2021/01-2023/12
2. 湖南省教育厅科学研究项目：20C1602，主持，2020/09-2023/06
3. 南华大学博士启动基金：190XQD141，主持
4. 南华大学教学与改革研究项目：2022ZD-XJG08, 2020ZD-XJG14，主持
七、代表性文章
(1)Shiying Ye; Xiangyan Hu; Shaowei Sun; Bo Su; Jiye Cai; Jinhuan Jiang*,Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.European Journal of Pharmacology.2024,974(17620),1-12.
(2) Xiangyan Hu, Sisi Huang, Shiying Ye, Jinhuan Jiang*,The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems,Current Pharmaceutical Biotechnology, 2024,25(6),655-664.
(3) Shiying Ye; Yi Gao;Xiangyan Hu; Jiye Cai; Shaowei Sun; Jinhuan Jiang*.Research progress and future development potential of Flammulina velutipes polysaccharides in the preparation process, structure analysis, biology, and pharmacology: A review.Int J Biol Macromol. 2024 May;267(Pt 1):131467.
(4) Shiying Ye; Shaowei Sun; Jiye Cai;Jinhuan Jiang* Advances in the Synthesis and Bioactivity of Polysaccharide Selenium Nanoparticles: A Review.Mini Rev Med Chem. 2024;24(16):1535-1554.
(5) Ye, Shi Ying; Sun, Shao Wei; Cai, Ji Ye; Jiang, Jin Huan*, Research progress and future
development potential of oridonin in pharmacological activities, Current Molecular Pharmacology ,2022.
(6)Jinhuan Jiang, Jiang Pi, Jiye Cai. Oridonin exhibits anti-angiogenic activity in human umbilical vein endothelial cells by inhibiting VEGF-induced VEGFR-2 signaling pathway. PatholRes Pract. 2020,216(8): 153031.
(7)Jinhuan Jiang, Jiang Pi, Hua Jin, Jiye Cai. Oridonin-induced mitochondria- dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/Mtor and Ras/Raf pathways.J Cell Biochem. 2019,120(3): 3736-3746.
(8)Jinhuan Jiang, Jiang Pi, Hua Jin, Fen Yang, Jiye Cai. Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function.Pathol Res Pract. 2018,214(5): 691-699.
(9)Jinhuan Jiang, Jiang Pi, Jiye Cai. Theadvancing ofzincoxidenanoparticles forbiomedicalapplications. Bioinorg Chem Appl. 2018,2018:1062562.
(10)Jinhuan Jiang, Jiang Pi, Hua Jin, Jiye Cai. Functional graphene oxide as cancer-targeted drug delivery system to selectively induce oesophageal cancer cell apoptosis. Artif Cells Nanomed Biotechnol. 2018, S3:297-30.
(11) Jiang Pi*,Jinhuan Jiang*, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai and Zheng W. Chen.GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways. DRUG DELIVERY, 2017. VOL. 24, NO. 1, 1549–1564
(12)Jiang JH, Yao S, Cai HH, Yang PH, Cai J.Synthesis and synergetic effects of chrysin-organogermanium (IV)complex as potential anti-oxidant. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5727-5732.
(13)Jiang JH, Jin H, Liu L, Pi J, Yang F, Cai J. Curcumin disturbed cell-cycle distribution of HepG2 cells via cytoskeletal arrangement.Scanning. 2013 Jul-Aug;35(4):253-260.
(14)Zhang L,Jiang JH, Luo JJ, Zhang L, Cai JY, Teng JW, Yang PH.A label-free electrochemiluminescence cytosensors for specific detection of early apoptosis.Biosens Bioelectron. 2013 Nov 15;49:46-52.
(15)江金环，张海涛，杨晓燕，孙少卫，郭紫芬.立德树人视野下药理学课程思政教育的探索，中国高等医学教育,2021(03):19-20.
(16)江金环，苏波，张海涛，杨晓燕，孙少卫，王姝之，郭紫芬.以学生为中心的BOPPPS教学模式下药理学课程思政教学设计，卫生职业教育，2022.