喻翠云,出生于1978年10月,土家族,中共党员,南华大学教授,博士研究生导师,留美归国学者,现任南华大学药学院院长,兼任新型抗体药物及其智能运输系统湖南省重点实验室副主任。先后荣获“全国三八红旗手”“湖南省三八红旗手”、“湖南省最美科技工作者”、湖南省自然科学杰出青年基金和湖南省委组织部优秀中青年专家等荣誉,牵头湖南省第二届“优秀研究生导师团队”—药剂学创新团队和南华大学“十二五”和“十三五”抗肿瘤药物研发科技创新团队牵头人,入选第二轮高层次卫生人才“225”工程——湖南省医学学科带头人、湖南省医学学科骨干人才、江苏省“江海英才计划”、南华大学“船山人才工程”和南华大学首批“青年英才计划”。主持国家科技部重点研发计划项目课题1项(2018YFB1900201),先后承担湖南省重点研发计划项目1项(2021SK2036),国家自然科学基金(含青年基金)2项(81471777、81102409)、湖南省自然科学基金杰出青年基金1项(2017JJ1024)等。在学术任职方面,担任中国抗癌协会肿瘤微环境专业委员会委员、湖南省欧美同学会理事、湖南省药学会第十五届理事会理事、国家自然科学基金委员会评审专家、教育部评审专家、湖南省科技厅评审专家、南华大学学术委员会委员,任Current Topics in Medicinal Chemistry杂志(SCI)客座主编等。主要创新性成果已经以第一作者/通讯作者身份在国际主流期刊如《Journal of Controlled Release》《ACS Applied Materials & Interfaces》、《Acta Biomaterialia》、《Molecular Pharmaceutics》等,累计以第一或通讯作者发表被SCI收录30多篇,经检索《ISI Web of Science》累计被引用逾600次,SCI“H-index”为15,被陈学思院士、美国三院院士Nicholas A. Peppasr等国内外知名专家大段引用、高度肯定,在国内外相关领域产生了重要的影响。已申请中国发明专利7项,授权4项;编写专著7部,其中主编SCI期刊2期,副主编教材、专著各1部,参编3部。
近几年主持的科研项目、课题:
1、湖南省重点研发计划课题,2021SK2036,AS1411介导的球形核酸生物大分子药物自传递体系关键技术研究,2021-2023,50-150,在研,主持。
2、国家重点研发计划课题,2018YFB190020 1,放射性废液膜蒸馏处理装置研制应用,2019/04-2023/03,2895万元,在研,主持。
3、湖南省自然科学杰出青年基金,2017JJ1024,生长抑素类似物修饰果胶-阿霉素纳米药物传递体系抗肝癌作用机制研究,2017/01-2019/12,30万元,在研,主持。
4、国家自然科学基金项目,81471777,肝癌细胞靶向性药物与miR-122共传输体系及其协同抗肿瘤作用机制研究,2015/01-2018/12,72万元,已结题,主持。
5、湖南省科学技术厅课题,2014GK3082,用于5-FU和MiR-122共传输的半乳糖化壳聚糖基纳米药物载体研究,2014/01-2015/09,5万元,已结题,主持。
6、国家自然科学基金项目,81102409,肝癌靶向性果胶基纳米载药体系的研究,2012/01-2014/12,20万元,已结题,主持。
近几年以通讯作者(含共同通讯作者)发表部分学术论文:
[1] Jinlei Peng, Ying Liu, Miao Zhang, Fangjun Liu, Liwei Ma, Cuiyun Yu*(通讯作者), Hua Wei*. One-pot fabrication of dual-redox sensitive, stabilized supramolecular nanocontainers for potential programmable drug release using a multifunctional cyclodextrin unit. J Control Release., 2021, 334, 290-302. (SCI, JCR Q1, IF= 9.776)
[2] Zhi Zheng, Ying Tan, Yi Li, Ying Liu, Guanghui Yi*, Cuiyun Yu*,(通讯作者)Hua Wei*. Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction. J Control Release., 2021, 335, 216-236. (SCI, JCR Q1, IF= 9.776)
[3] Xiao-Bo Nie, Cui-Yun Yu*(通讯作者), Hua Wei*. Precise modulation ofspatially distributed inorganic nanoparticles in block copolymers-based self-assemblies with diverse morphologies. Mater. Today Chem, 2021, 22. (SCI, JCR Q1, IF= 8.301)
[4] Zhi Zheng, Cuiyun Yu*(通讯作者),Hua Wei*. Injectable hydrogels as three-dimensional network reservoirs for osteoporosis treatment. Tissue Eng Part B Rev, 2021, 27(5) : 430-454. (SCI, JCR Q1, IF=6.389)
[5] Gui-Ying Kang, Wei Ma, Ming-Zhu Liu, Hai-Xi Luo, Cuiyun Yu*(通讯作者),Hua Wei* Expanding cyclic topology-based biomedical polymer panel:universal synthesis of hetero-"8"-shaped copolymers and topological modulation of polymer degradation. Macromol Rapid Commun, 2021, 42(17). (SCI, JCR Q1, IF=5.734)
[6] SiYue Tang, Hua Wei, CuiYun Yu *(通讯作者). Peptide-functionalized delivery vehicles for enhanced cancer therapy[J]. I Int J Pharm, 2021, 593 : 120141-.(SCI, JCR Q1, IF=5.873)
[7] Ya Xiang; Wen Huang; Cong Huang; Jinrong Long; Yangchun Zhou; Yufeng Liu; Siyue Tang, DongXiu He, XiangWen Tan, Hua Wei*, CuiYun Yu*(通讯作者). Facile fabrication of nanoparticles with dual-targeting ligands for precise hepatocellular carcinoma therapy in vitro and in vivo. Mol Pharm, 2020, 17(9) : 3223-3235. (SCI, JCR Q1, IF=4.939)
[8] Cheng-Hui Xu , Peng-Ju Yeab,Yang-Chun Zhou , Dong-Xiu Hea, Hua Wei *,Cui-Yun Yu*.(通讯作者)Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy. Acta Biomaterialia. 2020, 105, 1-14. (SCI, JCR Q1, IF=6.638)
[9] Mingqi Wang, Jinrong Long,Simin Zhang, Fangjun Liu, Xiaolong Zhang, Xianshuo Zhang, Lu Sun, Liwei Ma, Cuiyun Yu*(通讯作者)and Hua Wei*. Folate-targeted anticancer drug Delivery via a combination strategy of a micelle complex and reducible conjugation. ACS Biomater. Sci. Eng. 2020, 6, 1565-1572. (SCI, JCR Q1, IF=4.511)
[10] Yuping Liu, Yong Cong, Wei Ma, Guiying Kang, Chao Meng, Fangjun Liu, Cui yun Yu*(通讯作者)and Hua Wei*. Triple functional AB2 unit-modulated facile preparation of bioreducible hyperbranched copolymers. ACS Biomater. Sci. Eng. 2020, 6(5) : 2812-2821. (SCI, JCR Q2, IF=4.152)
[11] Lu Sun, Yang Zhou, Xufeng Zhou, Liwei Ma, Baoyan Wang, Cuiyun Yu*(通讯作者)and Hua Wei*. Synthesis of a triple-responsive double hydrophilic block copolymer prodrug using a reducible RAFT-ATRP double-head agent. ACS Applied Polymer Materials, 2020, 2(6) : 2126-2133. (SCI, JCR Q2, IF=4.089)
[12] Qian Ning, Yu-Feng Liu, Peng-Ju Ye, Pei Gao,Zhi-Ping Li ,SiYue Tang,Dong-Xiu He, Sheng-Song Tang,Hua Wei*and Cui-Yun Yu*.(通讯作者)Delivery of liver specific miRNA-122 using a targeted macromolecular prodrug toward synergistic therapy for hepatocellular carcinoma. ACS Applied Materials & Interfaces.2019, 11(11):10578-10588. (SCI, JCR Q1, IF=8.456)
[13] Guiying Kang, Lu Sun, Yuping Liu,Chao Meng, Wei Ma, Baoyan Wang, Liwei Ma, Cuiyun Yu*(通讯作者)and Hua Wei*. Micelles with cyclic poly(epsilon-caprolactone) moieties: greater stability, larger drug loading capacity, and slower degradation property for controlled drug release. Langmuir. 2019, 35, 12509−12517. (SCI, JCR Q2, IF=3.683)
[14] Xianshuo Zhangb Fangjun Liu, Xiaochen Li, Yunfei Tian, Liwei Ma, Cuiyun Yu*(通讯作者)and Hua Wei*.The fabrication of hybrid micelles with enhanced permeability for drug delivery via a diethoxymethylsilyl-based crosslinking strategy . Polym. Chem., 2019, 10,4529. (SCI, JCR Q1, IF=4.76)
[15] Huaxin Tan, Taoyu Wang, Yaru Shao, Cuiyun Yu*(通讯作者)and Lidan Hu*.Crucial Breakthrough of Functional Persistent Luminescence Materials for Biomedical and Information Technological Applications. Frontiers in Chemistry. 2019,7:387. (SCI, JCR Q2, IF=3.782)
[16] Xiaolong Zhang, Qi Hua, Pina Meng, Minggi Wang,Yunfei Wang, Lu Sun,Liwei Ma, Baoyan Wang, Cuiyun Yu*(通讯作者)and Hua Wei *.Fabrication of Biocleavable Crosslinked Polyprodrug Vesicles via Reversible Donor-Acceptor Interactions for Enhanced Anticancer Drug Delivery. Polym.Chem. 2019,21(10): 2666-2673. (SCI, JCR Q1, IF=4.76)