何隆薇,男,教授,博士生导师。2015获湖南大学化学专业博士学位,随后入职济南大学,历任讲师、副教授;2020年加入南华大学,入选药学院青年优秀人才。研究方向主要包括光功能染料、分子荧光探针的设计及生物医学成像,迄今以第一作者/通讯作者在Chem. Soc. Rev. (IF=40.44)、Chem. Sci. (2篇,IF=9.56)、ACS Appl. Mater. Interfaces (2篇,IF=8.45)、Chem. Comm. (5篇,IF=6.16)、Anal. Chem. (2篇,IF = 6.35)、Front. Bioeng. Biotechnol. (IF=5.98)、J. Mater. Chem. B (IF=6.33)、Chem.-Eur. J. (IF=5.16)等著名国际期刊上共发表18篇论文,其中JCR一区论文14篇、高被引论文2篇,总共被引用1100余次,单篇最高被引用次数为270余次,引用次数大于50的有7篇。主持国家自然科学基金青年项目、山东省自然科学基金博士项目、国家重点实验室开放基金、南华大学高层次人才项目等。
长期欢迎对本研究方向感兴趣的同学报考本课题组的博士和硕士研究生!联系方式:邮箱helongwei0110@163.com。
主持科研项目:
1.国家自然科学基金青年项目:编号21605059;新型单独及连续识别亚硝酰氢(HNO)/一氧化氮(NO)比率单荧光探针的设计、合成及生物成像应用研究;2017/01-2019/12;20万元。
2.山东省自然科学博士基金项目:编号ZR2016BB26;基于多信号模式荧光探针区分检测半胱氨酸/高半胱氨酸、谷胱甘肽和硫化氢及生物荧光成像研究;2016/11-2018/11;8万元。
3.南华大学高层次人才启动项目:编号201RGC012 /有机小分子荧光探针构建及肿瘤分子影像研究,2020/9-2025/9,300万。
代表性论文:
1.Longwei He, Baoli Dong, Yong Liu and Weiying Lin*,Fluorescent chemosensors manipulated by dual/triple interplaying sensing mechanisms,Chemical Society Reviews, 2016, 45(23): 6449−6461.(Highly Cited Paper,一区,IF =40.44)
2.Longwei He, Xueling Yang, Xiuqi Kong,Weiying Lin*,A multi-signal fluorescent probe for simultaneously distinguishing and sequentially sensing cysteine/homocysteine, glutathione, and hydrogen sulfide in living cells,Chemical Science, 2017,8(9):6257-6265.(Highly Cited Paper,一区,IF =9.55)
3.Longwei He, Weiying Lin*, Qiuyan Xu, Mingguang Ren, Haipeng Wei,Jianyong Wang,A simple and effective “capping” approach to readily tune the fluorescence of near-infrared cyanines,Chemical Science, 2015,6(8): 4530–4536.(一区,IF =9.55)
4.Longwei He,Yunzhen Yang, Weiying lin*,Rational design of a rigid fluorophore−molecular rotor-based probe for high signal-to-background ratio detection of sulfur dioxide in viscous system,Analytical Chemistry, 2019, 91(23), 15220−15228.(一区,IF =6.35)
5.Longwei He, Xueling Yang, Kaixin Xu and Weiying Lin*,Improvedaromaticsubstitution-rearrangement-basedratiometricfluorescentcysteine-specificprobe anditsapplication ofreal-timeimaging underoxidativestress inlivingzebrafish,Analytical Chemistry, 2017, 89(17): 9567–9573. (一区,IF =6.35)
6.Longwei He,Xueling Yang, Kaixin Xu, Yunzhen Yang, Weiying lin*,A multifunctional logic gate by means of a triple-chromophore fluorescent biothiol probe with diverse fluorescence signal patterns,Chemical Communications, 2017, 53(98):13168-13171.(一区,IF =6.16)
7.Longwei He,Xueling Yang, Kaixin Xu, WeiyingLin*,A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues,Chemical Communications, 2017, 53(29): 4080-4083. (一区,IF =6.16)
8.Longwei He, Qiuyan Xu, Yong Liu, Haipeng Wei, Yonghe Tang, Weiying Lin*,Coumarin-based Turn-On fluorescence probe for specific detection of glutathione over cysteine and homocysteine,ACS Applied Materials & Interfaces, 2015, 7(23): 12809−12813.(一区,IF =8.45)
9.Longwei He, Weiying Lin*, Qiuyan Xu,Haipeng Wei,A new strategy to construct FRET platform for ratiometric sensing hydrogen sulfide,Chemical Communications, 2015, 7(8): 12809−12813. (一区,IF =6.16)
10.Longwei He, Weiying Lin*, Qiuyan Xu, Haipeng Wei,Auniquetype ofpyrrole-basedcyaninefluorophores withturn-on andratiometricfluorescencesignals atdifferent pHregions forsensing pH inenzymes andlivingcells,ACS Applied Materials & Interfaces,2014, 6(24): 22326−22333. (一区,IF =8.45)
11. Songjiao Li, Dan Cheng,Longwei He*, Lin Yuan, Recent Progresses in NIR-I/II Fluorescence Imaging for Surgical Navigation,Frontiers in Bioengineering and Biotechnology, 2021, 9, 768698. (一区,IF =5.98)
12. Xiangyang Gong, Dan Cheng*, Wei Li*, Yang Shen, Rong Peng, Ling Shi,*Longwei He*, Lin Yuan, A highly selective ratiometric molecular probe for imaging peroxynitrite during drug-induced acute liver injury,Journal of Materials Chemistry B, 2021, 9, 8246–8252. (一区,IF =6.33)
13. Songjiao Li, Ke Yang, Jiayu Zeng, Yuqing Xia, Dan Cheng,*andLongwei He,*A NIR-emissive probe with remarkable Stokes shift for CO-releasing molecule-3 detection in cells and in vivo,Analyst, 2022, DOI, 10.1039/d2an00038e.